Ziptide--生命科学试剂-MCE.pdf

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Ziptide

Cat.No.:HY-P10367

CASNo.:518069-98-2

分⼦式:C₆₅H₁₀₉N₁₉O₁₉

分⼦量:1460.68

Sequence:Lys-Lys-Leu-Asn-Arg-Thr-Leu-Ser-Phe-Ala-Glu-Pro-Gly

SequenceShortening:KKLNRTLSFAEPG

作⽤靶点:MAPKAPK2(MK2);CheckpointKinase(Chk);AMPK

作⽤通路:MAPK/ERKPathway;CellCycle/DNADamage;Epigenetics;

PI3K/Akt/mTOR

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Ziptide是多种激酶的底物，如MAPK蛋⽩激酶2(MAPKAPK2,Km=5μM)、MAPKAPK3(Km=30μM)、

PARK(Km=40μM)、checkpointkinase1(Chk1,Km=5μM),AMP激活蛋⽩激酶(AMPK,Km=75μM)以

及钙/钙调素依赖性蛋⽩激酶II(CamKII,Km=300μM)。

REFERENCES

[1].Ross,H.,etal.Anon-radioactivemethodfortheassayofmanyserine/threonine-specificproteinkinases.BiochemJ.366(Pt3),977-981

(2002).

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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