ZP3022--生命科学试剂-MCE.pdf

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ZP3022

Cat.No.:HY-P10341

分⼦式:C₁₉₉H₂₉₄N₄₈O₆₁S

分⼦量:4366.81

Sequence:His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Gl

u-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-(8Ad

o)-(8Ado)-Tyr-Gly-Trp-Leu-Asp-Phe-NH28Ado:8-amino-3,6-di

oxaoctanoicacid

SequenceShortening:HGEGTFTSDLSKQMEEEAVRLFIEWLKN-(8Ado)-(8Ado)-

YGWLDF-NH28Ado:8-amino-3,6-dioxaoctanoicacid

作⽤靶点:GCGR

作⽤通路:GPCR/GProtein

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性ZP3022是⼀种胰⾼⾎糖素样肽-1(GLP-1)和胃泌素的双重激动剂，具有持续改善⾎糖控制的能⼒。同时，

ZP3022还能有效增加β细胞的质量、促进β细胞增殖，并提升平均胰岛质量。ZP3022可以⽤于抗糖尿病的

研究[1]。

REFERENCES

[1].DalbøgeLS,etal.ThenovelGLP-1-gastrindualagonistZP3022improvesglucosehomeostasisandincreasesβ-cellmasswithout

affectingisletnumberindb/dbmice.JPharmacolExpTher.2014;350(2):353-360.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.