- 1、本文档共84页,可阅读全部内容。
- 2、有哪些信誉好的足球投注网站(book118)网站文档一经付费(服务费),不意味着购买了该文档的版权,仅供个人/单位学习、研究之用,不得用于商业用途,未经授权,严禁复制、发行、汇编、翻译或者网络传播等,侵权必究。
- 3、本站所有内容均由合作方或网友上传,本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺!文档内容仅供研究参考,付费前请自行鉴别。如您付费,意味着您自己接受本站规则且自行承担风险,本站不退款、不进行额外附加服务;查看《如何避免下载的几个坑》。如果您已付费下载过本站文档,您可以点击 这里二次下载。
- 4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等,请点击“版权申诉”(推荐),也可以打举报电话:400-050-0827(电话支持时间:9:00-18:30)。
1FungalPathogens:
Mycology
WeiZhao,Ph.D.MedicalMicrobiologyCenterCollegeofMedicalSciencesQingdaoUniversity
2Objectives:Abasicunderstandingoffungiandthediseasestheycause.List4characteristicsoffungi.Definemajorcategoriesofmycosis.Dimorphicfungiandpathogenesis.EIDandopportunisticfungi.
3
4IntroductiontoMycologyBeer,Wine,BreadVinegar,CheeseGourmetmushroomsAntibioticsBiodegradationDiseaseOftheapproximately70,000recognizedspeciesoffungi,about300areknowntocausehumaninfections.Ringworminfectiononleg
5
6
7
8
9MajorCategoriesofFungalInfectionInfection:passtheresistancebarriersofthehumanbody.classifiedaccordingtothetissuelevelsinitiallycolonizedSuperficial:limitedtotheoutermostlayersoftheskinandhair.Cutaneous:extenddeeperintotheepidermis,aswellasinvasivehairandnaildiseases.Subcutaneous–Lymphatic:involvingthedermis,subcutaneoustissues,muscleandfascia
10MajorSpeciesCauseFungalInfectionSuperficial:Malasseziafurfur,Tineaversicolor;TineaCutaneous:Trichophyton,Epidermophyton,Microsporum(Tinea-causingdermatophytes)Candidaalbicans(thrushdiaperrash)Subcutaneous-Lymphatic:Sporothrixschenckii(Sporotrichosis,Rosegrowersdisease”),Chromoblastomycosis
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26Sporothrixschenckiihasayeastformat37°C.
YoungcoloniesofSporothrixschenckiiremainwhiteforsometimeat25°C.
27
28
29SystemicMycosesInvolveskinanddeepvisceraMayewidelydisseminatedPredilectionforspecificorgans
30EndemicMycosesGeographicallyrestrictedtospecificareasofendemicity.Coccidioidesspp.andHistoplasmaspp.exitindrysoil;thehabitsofBlastomycesspp.andParacoccidioidesspp.havenotbeenclearlydefined.Infectionsinitiateinthelungs,afewleadtodisease,mayinvolvedisseminationtootherorgans.Nottransmissibleamonghumans(animals).Dimorphicfungi.
31DimorphicFungiYeastFormParasiticformTissuefo
文档评论(0)