2013亚太呼吸会-(英)MDR致病菌引起的社区感染.pptx

2013亚太呼吸会-(英)MDR致病菌引起的社区感染.pptx

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Infectionsinthecommunitycausedbymulti-drugresistantpathogensFrancescoBlasiDepartmentofPathophysiologyandTransplantation

UniversityofMilanItaly

MeetingtheChallengeofAntimicrobialResistance(AMR)andRespiratoryInfections

CurrentStatusTypeofInfectionTuberculosisMDR-XDRstrains,fewnewdrugsavailableGrampositivesNofurtherincreaseinresistance,newdrugsavailableGramnegativesDramaticincreaseinresistance,lackofdrugdevelopmentFungalinfectionRoleofaspergillusinfectioninimmunocompetentpatientsunclearViralinfectionIncreasingdetectionrateduetonewPCRtechnologyClinicalimportanceunclear

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5CausesofMDRPatientmismanagement

OutcomesofMDR-TBtreatmentForMDR-TBpatientsstartedontreatmentin2008*0%20%40%60%80%100%Kazakhstan(2268)Turkey(263)Uzbekistan(294)Ecuador(210)Georgia(417)DemocraticRepublicoftheCongo(202)Philippines(520)Namibia(221)RussianFederation(1537)Brazil(444)Kyrgyzstan(262)RepublicofMoldova(522)SouthAfrica(4383)Romania(816)SuccessDiedFailedDefaultedNotevaluated*Incountriesreportingoutcomesfor200MDR-TBcaseswith20%unevaluated(cohortsizeshownbelowcountrynames)

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13

Consilium:whatitisWHOrecommendation:M/XDR-TBcasesmanagedbyspecializedteam,includingcomplementarymedicalprofessionalsabletocoverseveralperspectives(clinical,bothforadultsandchildren;surgical;radiological;publichealth;psychological;nursing,etc.)

TheideaCreateaERS-managedwebplatformtoallowaEuropeanclinician,freecost,toloadpt’sdataandreceivein1wsuggestionsby2expertsonhowtomanageadifficult-totreat-TBcaseincollaborationwithWHO(MoU)andECDC

ThepotentialityTobecomeTHEworlde-serviceTosupportfollow-upofTBpatientswithEurope

Theseactionhavebeendefinedbasedthereviewingprocess:Descriptionoftheplatform(1)

Descriptionoftheplatform(2)Theplatformworksonadashboardbase:

Accordingtoitsrole(Director,AreaC

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