Pantinin-3-生命科学试剂-MCE.pdf

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Pantinin-3

Cat.No.:HY-P10511

CASNo.:2383115-06-6

分⼦式:C₇₂H₁₁₄N₁₆O₁₈

分⼦量:1491.77

Sequence:Phe-Leu-Ser-Thr-Ile-Trp-Asn-Gly-Ile-Lys-Ser-Leu-Leu

SequenceShortening:FLSTIWNGIKSLL

作⽤靶点:Apoptosis

作⽤通路:Apoptosis

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Pantinin-3是⼀种存在于帝王蝎(Pandinusimperator)毒液中具有抗肿瘤活性的抗菌肽。Pantinin-3对乳腺癌

细胞(MDA-MB-231)和前列腺癌细胞(DU-145)显⽰出选择性的毒性。Pantinin-3能够诱导肿瘤细胞发⽣凋亡(

apoptosis)。Pantinin-3可⽤于癌症领域的研究[1]。

REFERENCES

[1].CruscaJrE,etal.BiophysicalcharacterizationandantitumoractivityofsyntheticPantininpeptidesfromscorpionsvenom[J].

BiochimicaetBiophysicaActa(BBA)-Biomembranes,2018,1860(11):2155-2165.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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