L-NMMA-citrate-Methylarginine-citrate-生命科学试剂-MCE.pdf

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Inhibitors•ScreeningLibraries•Proteins

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L-NMMAcitrate

Cat.No.:HY-18732B

CASNo.:209913-88-2

Synonyms:Methylargininecitrate;Tilargininecitrate

分⼦式:C₁₃H₂₄N₄O₉

分⼦量:380.35

作⽤靶点:NOSynthase;EndogenousMetabolite

作⽤通路:Immunology/Inflammation;MetabolicEnzyme/Protease

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性L-NMMAcitrate竞争性地拮抗L-精氨酸，从⽽抑制⼀氧化氮(NO)的产⽣。L-NMMA在实验环境中⽤作⼀氧化

氮合酶(NOsynthase)拮抗剂[1]。

客户使⽤本产品发表的科研⽂献

•NatImmunol.2023Jan;24(1):162-173.

•NatCommun.2021May10;12(1):2587.

•CellMolGastroenterolHepatol.2021;11(3):683-696.

•FrontCellDevBiol.2021Dec23;9:741911.

•EurJImmunol.2020Jun;50(6):795-808.

Seemorecustomervalidationsonwww.MedChemE

REFERENCES

[1].FreyC,etal.,L-thiocitrulline.Astereospecific,heme-bindinginhibitorofnitric-oxidesynthases.JBiolChem.1994Oct

21;269(42):26083-91.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.