Pteroylhexaglutamate-PteGlu6-生命科学试剂-MCE.pdf

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Pteroylhexaglutamate

Cat.No.:HY-138031

CASNo.:35409-55-3

Synonyms:PteGlu6

分⼦式:C₄₄H₅₄N₁₂O₂₁

分⼦量:1086.97

作⽤靶点:EndogenousMetabolite

作⽤通路:MetabolicEnzyme/Protease

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Pteroylhexaglutamate(PteGlu6)可抑制50%的T2噬菌体诱导的合成酶(在没有Mg2+的情况下，浓度为0.6

μM)。Pteroylhexaglutamate是蝶酰聚⾕氨酸⽔解酶的底物，可⽤于监测蝶酰聚⾕氨酸⽔解酶的活性。

IC50TargetHumanEndogenousMetabolite

REFERENCES

[1].MaleyGF,etal.Differentialinhibitionofhostandviralthymidylatesynthetasesbyfolylpolyglutamates.JBiolChem.1979Aug

25;254(16):7485-7.

[2].SeyoumE,etal.Propertiesoffoodfolatesdeterminedbystabilityandsusceptibilitytointestinalpteroylpolyglutamatehydrolaseaction.J

Nutr.1998Nov;128(11):1956-60.

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