Serum-thymic-factor-acetate-Thymulin-acetate-生命科学试剂-MCE.pdf

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Serumthymicfactoracetate

Cat.No.:HY-P3206A

CASNo.:125117-65-9

Synonyms:Thymulinacetate;Thymicfactoracetate

分⼦式:C₃₅H₅₈N₁₂O₁₇

分⼦量:918.91

Sequence:{Pyr}-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn

SequenceShortening:{Pyr}-AKSQGGSN

作⽤靶点:ERK

作⽤通路:MAPK/ERKPathway;StemCell/Wnt

储存⽅式:Sealedstorage,awayfrommoisture

Powder-80°C2years

-20°C1year

Insolvent-80°C6months

-20°C1month

BIOLOGICALACTIVITY

⽣物活性Serumthymicfactoracetate(Thymulinacetate)是Serumthymicfactor(HY-P3206)的醋酸盐形式。Serum

thymicfactoracetate(Thymulin)是⼀种锌依赖性免疫调节肽激素，可由胸腺上⽪细胞产⽣。Serumthymic

factoracetate刺激垂体释放激素，表现出促垂体活性。Serumthymicfactoracetate通过抑制ERK激活保护

⼤⿏免受Cephaloridine(HY-B2072)-引起的肾毒性。Serumthymicfactoracetate具有抗糖尿病、抗炎和镇

痛活性。Serumthymicfactoracetate可⽤于内分泌、⽣殖、神经退⾏性和炎症性疾病的研究。

REFERENCES

[1].PardoJ,etal.Physiology,molecularbiologyandtherapeuticpotentialofthethymicpeptidethymulin[J].PhysiologicalMiniReviews

(PMR),2012,6.

[2].DardenneM,etal.Roleofthymulinoritsanalogueasanewanalgesicmolecule.AnnNYAcadSci.2006Nov;1088:153-63.

[3].KohdaY,etal.Protectiveeffectofserumthymicfa