神经导航钻孔引流联合尿激酶治疗基底节脑出血的效果分析.docx

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神经导航钻孔引流联合尿激酶治疗基底节脑出血的效果分析

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丁观福++陈金明++王海滨++曾照彬

[摘要]目的探讨神经导航钻孔引流术联合尿激酶治疗基底节脑出血的效果。方法回顾2015年1月～2017年1月我科神经导航下颅骨钻孔引流术后给予尿激酶治疗的36例高血压基底节脑出血患者的临床资料，对其手术效果、并发症、临床预后进行评价总结。结果纳入研究的36例患者，2例死于呼吸衰竭，1例死于心脏疾病，另有5例患者出现手术相关并发症，包括引流管异位1例，血肿腔再出血2例，穿刺道出血1例，颅内积气1例，随访观察3个月，有22例的患者取得较好的治疗效果（格拉斯哥预后评分3分）。结论神经导航下钻孔引流术后给予尿激酶治疗基底节脑出血是简单、安全有效的治疗方案。

[关键词]基底节出血；神经导航；钻孔引流；尿激酶

[]R651.1[]A[]1674-4721（2017）11（a）-0039-04

Clinicalefficacyofneuronavigation-assistedminimallyinvasiveoperationandsubsequentfibrinolysisusingUrokinaseonhypertensivebasalgangliahemorrhage

DINGGuan-fuCHENJin-minWANGHai-bingZENGZhao-Bin

DepartmentofNeurosurgery，theFirstAffiliatedHospitalofGannanMedicalCollege，JiangxiProvince，Ganzhou341000，China

[Abstract]ObjectiveToexploretheeffectofacombinationofneuronavigation-assistedminimallyinvasiveoperationandUrokinaseonthetreatmentofhypertensivebasalgangliahemorrhage.MethodsAretrospectiveanalysiswasperformedbyincluding36patientswithhypertensivebasalgangliahemorrhagethatweretreatedbyUrokinasefollowingneuronavigation-assistedminimallyinvasiveoperationfromJanuary2015toJanuary2017inourhospital.Surgicalresults，procedure-relatedcomplicationsandclinicaloutcomeswereevaluatedsubsequently.ResultsAtotalof36patientswereenrolledinthestudy，2patientsdiedofrespiratoryfailure（twopatients）and1patientdiedofheartdisease.Inaddition，5patientsoccurredsurgicalcomplications，including1caseofectopicdrainage，2casesofrebleedingintoahematomacavity，1caseofhemorrhageinpuncturetract，and1caseofintracranialpneumatocele.Incorporatedpatientswerefollowedupfor3months，22patientsachievedbettertreatmentresults（Glasgowoutcomescalescore3scores）.ConclusionNeuronavigation-assistedminimallyinvasiveoperationandsubsequentfibrinolysisusingUrokinaseisasimple，safeandeffectiveprocedureforthetreatmentofhypertensivebasalgangliahemorrh