凝血功能检验对心脑血管疾病患者预后的价值分析.docx

?

?

凝血功能检验对心脑血管疾病患者预后的价值分析

?

?

陈东梅

【摘要】目的分析凝血功能檢验对心脑血管疾病患者预后的价值。方法73例心脑血管疾病患者纳入研究组，根据预后情况不同将其分为A组（预后良好，51例）与B组（病残，22例）;另将本院同时期行常规体检的73例健康者纳入对照组，所有受试者均行凝血功能检验。对比研究组与对照组的凝血功能指标以及A组与B组的凝血功能指标。结果治疗前，研究组的凝血酶原时间、凝血酶时间、活化部分凝血活酶时间均短于对照组，纤维蛋白原、抗凝血酶Ⅲ、D-二聚体、内皮素-1、纤溶酶原激活抑制物-1、血栓调节蛋白均高于对照组，差异有统计学意义（P0.05）。A组的凝血酶原时间、凝血酶时间、活化部分凝血活酶时间、纤维蛋白原、抗凝血酶Ⅲ、D-二聚体、内皮素-1、纤溶酶原激活抑制物-1、血栓调节蛋白均优于B组，差异有统计学意义（P

【关键词】凝血功能;心脑血管疾病;预后

DOI：10.14163/j.cnki.11-5547/r.2020.31.008

Thevalueofcoagulationtestintheprognosisofpatientswithcardiovascularandcerebrovasculardiseases??CHENDong-mei.SouthernUniversityofScienceandTechnologyHospital，Shenzhen518055，China

【Abstract】Objective??Toanalyzethevalueofcoagulationtestintheprognosisofpatientswithcardiovascularandcerebrovasculardiseases.Methods??Therewere73patientswithcardiovascularandcerebrovasculardiseasesselectedastheresearchgroup，andtheyweredividedintogroupA（51cases，goodprognosis）andgroupB（22cases，disability）.73healthysubjectswhounderwentroutinephysicalexaminationinourhospitalatthesametimewereincludedinthecontrolgroup，andallsubjectsunderwentcoagulationtest.Thecoagulationfunctionindexesoftheresearchgroupandthecontrolgroup，aswellasthecoagulationfunctionindexesofgroupAandgroupBwerecompared.Results??Beforetreatment，theprothrombintime，thrombintime，activatedpartialthrombintimeoftheresearchgroupwereshorterthanthoseofthecontrolgroup，andfibrinogen，antithrombinⅢ，D-dimer，endothelin-1，plasminogenactivationinhibitor-1，thrombomodulinwerehigherthanthoseofthecontrolgroup，andthedifferencewasstatisticallysignificant（P0.05）.Theprothrombintime，thrombintime，activatedpartialthrombintime，fibrinogen，antithrombinⅢ，D-dimer，endothelin-1，plasminogenactivatorinhibitor-1，thrombomodulinofgroupAwerebetterthanthoseofgroupB，andthedifferencewasstatisticallysignificant（P

【K