前列腺和膀胱颈部肿瘤同期电切术后吡柔比星灌注疗效分析.docx

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前列腺和膀胱颈部肿瘤同期电切术后吡柔比星灌注疗效分析

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【摘要】目的：探讨前列腺和膀胱颈部肿瘤同期电切术后吡柔比星灌注的对比疗效。方法：选择我院自2016年1月~2017年1月期间，住院部所收治的前列腺增生合并膀胱颈部肿瘤患者共计40例作为研究对象，按照计算机随机方法进行分组，20例患者被纳入观察组，20例患者被纳入对照组。对照组20例患者同期实施前列腺电切术以及表浅性膀胱颈部肿瘤电切术。观察组20例患者手术方案与对照组完全一致，术后加用吡柔比星灌注干预。结果：观察组患者随访期间不良反应发生率为15.00％（3/20），明显低于对照组，数据组间对比存在明显差异，P＜0.05，具有统计学意义。结论：前列腺和膀胱颈部肿瘤同期电切术后吡柔比星灌注有非常好的临床价值，对降低不良反应发生率，减少肿瘤复发率而言效果突出，望引起重视。

【关键词】膀胱肿瘤；前列腺；电切术；吡柔比星灌注

Efficacyanalysisofintravesicalinstillationofpirarubicinafterconcurrenttransurethralresectionofprostateandbladdernecktumors

HuGuijin

Departmentofgeneralsurgery,No.211HospitalofPLA,Heilongjiang150080,Harbin,China)

【Abstract】Objective:Tocomparetheefficacyofpirarubicinperfusionaftertransurethralresectionofprostateandbladdernecktumors.Methods:inourhospitalfromJanuary2016~2017yearinJanuaryduringthehospitalizationofbenignprostatichyperplasiacomplicatedwithbladderneckcancerpatientsadmittedtotheDepartmentofatotalof40casesastheresearchobject,weregroupedaccordingtotherandommethod,20patientswereincludedintheobservationgroup,20patientswereincludedinthecontrolgroup.Thecontrolgroupconsistedof20patientswhounderwenttransurethralresectionoftheprostateandsuperficialbladdertumorresectionatthesametime.Intheobservationgroup,theoperationplanof20patientswasexactlythesameasthatofthecontrolgroup.Results:theincidenceofadversereactionsintheobservationgroupwas15%(3/20),whichwassignificantlylowerthanthatofthecontrolgroup,andtherewasasignificantdifferencebetweenthetwogroups,P0.05,whichwasstatisticallysignificant.Conclusion:intravesicalinstillationofpirarubicinaftersimultaneoustransurethralresectionofprostateandbladdernecktumorhasverygoodclinicalvalue.Itcanreducetheincidenceofadverseeventsandreducetherecurrencerateoftumor.

【Keywords】bladdertumor;