LAA型脑梗死患者颈动脉斑块稳定性的危险因素分析.pdfVIP

ModernScientificInstrumentsVol.40No.4Aug.2023

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LAA型脑梗死患者颈动脉斑块稳定性的危险因素分析

随旭朱瑞丁笑笑

（安徽医科大学合肥第三临床学院（合肥市第三人民医院）神经内科，安徽合肥230022）

摘要目的：探究LAA型脑梗死患者颈动脉斑块稳定性的危险因素。方法：选取75例急性LAA型脑梗死患者

为观察组，同期体检健康人群50例作为对照，比较各指标对LAA型脑梗死患者斑块稳定性的诊断价值。结果：不

稳定斑块组与稳定斑块组血UA、Hcy、CRP水平及均高于无斑块组及对照组，且斑块积分均高于稳定斑块组（

P0.05）；

血UA、Hcy、CRP水平及三者联合检测时诊断不稳定斑块的AUC分别为0.816、0.747、0.883、0.915。结论：血UA、

Hcy及CRP水平是预测急性LAA型患者颈动脉不稳定性斑块形成及动脉粥样硬化严重程度的可行性指标。

关键词脑梗死；大动脉粥样硬化；斑块稳定性；血尿酸；同型半胱氨酸；C-反应蛋白

Relationshipbetweencarotidplaquestabilityandserumuricacid,homocysteineand

C-reactiveproteininpatientswithacutelarge-arteryatheroscleroticcerebralinfarction

SuiXu;ZhuRui;DingXiaoxiao

(DepartmentofNeurology,TheThirdClinicalCollegeofHefei,AnhuiMedicalUniversity,Hefei230041,China)

AbstractObjective:ExploringriskfactorsforcarotidplaquestabilityinpatientswithLAAcerebralinfarction.

Methods:Seventy-fivepatientswithacuteLAAcerebralinfarctionwereselectedastheobservationgroup,and50healthy

patientsinthesameperiodofphysicalexaminationwereusedascontrolstocomparethediagnosticvalueofeachindexon

plaquestabilityinpatientswithLAAcerebralinfarction.Results:ThelevelsofUA,HcyandCRPintheunstableplaque

groupandthestableplaquegroupwerehigher,andtheplaquescorewashigher(P0.05);theAUCforthediagnosisof

unstableplaquewas0.816,0.747,0.883and0.915forbloodUA,Hcy,CRPlevelsandthecombinationofthethreetests,

respectively.Conclusion:BloodUA,Hcy