乙肝两对半的解读课件.pptVIP

Secondliverhalf-and-halhinterpretatino

?乙肝两对半的定义TheDefinitinoOfSecongLiverTwoHalf-and-Half

?乙肝两对半是国内医院最常用的乙肝病毒(HBV)感染检测血清标志物。(Secondlivertwohalf-and-halfisthemostcommonlyusedindomestichospitalofhepatitisbvirus(HBV)infectiondetectionserummarker)?⑤乙肝核心抗体（抗-HBc）测定两种抗原和三种抗体，也就是俗称的“两对半”。Determinationoftwokindsofantigensandthreekindsofantibody,alsoknownasthetwohalf-and-half.

Big3thisworldandsmall3thisworld?“大三阳”是指“乙肝两对半”化验结果为表面抗原、e抗原和核心抗体检测均是阳性。一般说明病毒复制水平高、传染性强。Big3thisworldreferstosecondlivertwohalf-and-halftestresultsforthesurfaceantigen,eantigenandcoreantibodytestsarepositive.Generaldescriptionswithhigh-levelviralreplicationandinfectivity.?“小三阳”是指“乙肝两对半”化验结果为表面抗原、E抗体和核心抗体检测均是阳性。一般说明病毒复制水平相对较低、传染弱。Whatissmall3thisworldsmall3thisworldreferstosecondlivertwohalf-and-halftestresultsforthesurfaceantigen,Eantibodyandcoreantibodytestsarepositive.Generaldescriptionsviralreplicationlevelisrelativelylowandweak.可见大三阳和小三阳的区别主要在病毒复制活跃程度上，但并不表示“大三阳”一定比“小三阳”病情严重，临床研究证实，有些小三阳患者更容易转化为肝癌。在治疗上，如果是乙肝患者且HBVDNA含量高，大三阳和小三阳的区别不大，都要以抗病毒治疗为主，辅助抗炎保肝，抗纤维化治疗。Visiblebig3thisworldandsmall3thisworlddifferenceismainlyintheviralreplicationactivity,butitdoesntmeanthebig3thisworldthansmall3thisworldthediseaseissevere,clinicalstudieshaveconfirmedthatsomesmall3thisworldaremorelikelytobeconvertedintolivercancerpatients.Intreatment,ifishepatitisbpatientsandhbvdnacontenthigh,thedifferencebetweenbig3thisworldandsmall3thisworldisnotbig,togiveprioritytowithantiviraltherapy,anti-inflammatory,protectingliver,auxiliaryantifibrosistreatment.

血液传播（Bloodtransmission)：如输入被感染的全血、血浆、血清或其它血制品，或其他血源性注射传播。Suchasinputofwholeblood,plasma,seruminfectedorotherbloodproducts,orotherblood-bornespreadofinjection性传播(Sexuallytransmission)：性滥交、同性恋和异性恋之间的亲密性行为是重要的乙肝病毒传播途径，这种传播亦包括家庭夫妻间的传播，夫妻之间的无防御措施的性行为传播率大概在14%左右