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LungCancerProf.WenjianhuDept.CardiothoracicSurgeryClinicalCollege,FirstAffiliatedHospitalChongqingUniversityofMedicalSciencesLungcancer
ContentsAnatomyIntroductionEtiologyPathologyClinicalPresentationDiagnosisStagingDifferentialDiagnosisTreatmentPrognosisSummaryDept.CardiothoracicsurgeryLungcancer
AnatomyDept.CardiothoracicsurgeryLungcancer
Dept.CardiothoracicsurgeryLungcancerRight:3lobes,10segments
Left:2lobes,10segments
Themainfunctionofthelungsisgasexchange.
IntroductionDept.CardiothoracicsurgeryLungcancer
Dept.CardiothoracicsurgeryLungcancerDefinition:Lungcancerisamalignancyofthelung.Itischaracterizedbyunregulatedreplicationofcellscreatingtumors.Today,wearegoingtostudyprimarylungcancer.Synonyms:Cancerofthelungs;Carcinomaofthelungs;Bronchogeniccarcinoma
EpidemiologyLungCancerWorldwide:mostcommoncancer2,000,000casesperyearChina:Leadingcauseofcancerdeathestimated500,000deaths2002
EtiologyDept.CardiothoracicsurgeryLungcancer
Whatcauseslungcancer?Multipleexposuretocarcinogens(cancer-causingagents)resultsindamagetoDNAinthecellsofthelung.Dept.CardiothoracicsurgeryLungcancer
Cigarettesmokingisbyfarthebiggestcarcinogenforthedevelopmentoflungcancer.responsiblefor85percentofalllungcancers.Dept.CardiothoracicsurgeryLungcancer
Otherriskfactorsincludethefollowing:FamilyhistoryEnvironmentalandoccupationalexposuretocertainsubstancesExposuretoexcessiveradiationPreviousLungdiseasesPoordietDept.CardiothoracicsurgeryLungcancer
PathologyDept.CardiothoracicsurgeryLungcancer
Dept.CardiothoracicsurgeryLungcancerLungCancerPathologicClassificationSMALLCELL~18%(15~25%)(SCLC)NON-SMALLCELL~82%(NSCLC)squamouscell~40%adenocarcinoma~30
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