乌兹别克斯坦yunusov植物质化学structure from astragalus chivensis结构来自黄芪.pdfVIP

ChemistryofNaturalCompounds,Vol.43,No.5,2007

STRUCTUREOFCYCLOCHIVINOSIDEC

FROMAstragaluschivensis

T.Kh.NaubeevandK.K.UteniyazovUDC547.918:547.926

ThenewcycloartaneglycosidecyclochivinosideC,24S-cycloartan-3β,6α,16β,24,25-pentaol3,16-di-O-β-D-

glucopyranoside,wasisolatedfromtheaerialpartofAstragaluschivensis.Thestructuresoftheisolated

compoundswereestablishedbychemicaltransformationsandPMRand13CNMRspectra.

Keywords:cycloartanes,cyclocanthogenin,cyclochivinosideC,cyclosiversiosideE,cyclosiversigenin.

IncontinuationofresearchoncycloartanetriterpenoidsfromplantsofthegenusAstragalus[1],weisolatedfromthe

butanolextractofBunge(Leguminosae)cyclosiversiosideE(1)[2,3]andanewglycosidiccompoundthatwecalled

A.chivensis

cyclochivinosideC(2).

ThePMRspectrumofcontainedinthestrong-fieldregionresonancesforprotonsofsevenmethylsat1.42,1.40,1.61,

1

1.40,1.11,1.89,and1.40ppmandfortwoanomericprotonsat4.83and4.81ppm.The13CNMRspectrumof1had

resonancesfortwoanomericCatomsat107.7and105.8ppm.

Thesedataindicatedthatwasabioside.

1

ThestructureofwasconfirmedconclusivelyusingPMRand13CNMRandtwo-dimensionalspectra.Theyagreed

1

withthosereportedforcyclosiversiosideE[2,3].

ThepresenceinthePMRspectrumofglycoside(Table1)of1Hdoubletsat0.22and0.54ppmforanABsystem

2

typicalofa1,1,2,2-tetrasubstitutedthree-memberedringandresonancesforsevenmethylsathighfieldindicatedthatthis

c