腹腔镜胆囊切除术治疗结石性胆囊炎合并轻症急性胆源性胰腺炎的手术时机研究-国际医学与数据杂志.docx

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腹腔镜胆囊切除术治疗结石性胆囊炎合并轻症急性胆源性胰腺炎的手术时机研究

【摘要】目的研究腹腔镜胆囊切除术（LC）治疗结石性胆囊炎合并轻症急性胆源性胰腺炎（MABP）的合适手术时机，并评估其安全性和临床疗效。方法选取本院2020年6月～2023年6月结石性胆囊炎合并MABP患者共86例，随机分为实验组和对照组，实验组患者在入院后48～72小时内行LC治疗，对照组患者待胰腺炎症状明显缓解后1～2周内接受LC治疗。比较两组的手术时间、术后住院时间、围手术期并发症（胆漏、出血、切口感染、胆管损伤等）发生率、中转剖腹率、总住院时间、总医疗费用以及胰腺炎复发率等指标。结果两组手术均获成功，无严重并发症及死亡；两组的围手术期并发症发生率、中转剖腹率、胰腺炎复发率、手术时间均无显著差异（P＞0.05）；术后住院时间：实验组较对照组显著延长（P＜0.05）；总住院时间：实验组较对照组显著缩短（P＜0.05）；总医疗费用：实验组较对照组显著降低（P＜0.05）。结论结石性胆囊炎合并轻症急性胆源性胰腺炎患者在入院48～72小时内行腹腔镜胆囊切除术是安全有效的，临床疗效满意。

【关键词】腹腔镜胆囊切除术；结石性胆囊炎；轻症急性胆源性胰腺炎；手术时机【基金项目】浙江省新昌县科技计划（JFZC2102）

【收稿日期】2024年7月2日【出刊日期】2024年9月26日【DOI】10.12208/j.ijmdLaparoscopiccholecystectomyforthetreatmentofcalculouscholecystitiscomplicatedwithmildacutebiliarypancreatitis:astudyonthetimingofoperation

【Abstract】ObjectiveToevaluatethesafetyandclinicalefficacyoflaparoscopiccholecystectomyforthetreatmentofcalculouscholecystitiscomplicatedwithmildacutebiliarypancreatitis.MethodsAtotalof86patientswithcalculouscholecystitiscombinedwithmildacutebiliarypancreatitiswereselectedfromourhospitalfromJune2020toJune2023,andwererandomlydividedintoexperimentalgroupandcontrolgroup.PatientsintheexperimentalgroupreceivedLCtreatmentwithin48to72hoursofadmission,andpatientsinthecontrolgroupreceivedLCtreatmentwithin1to2weeksaftersignificantreliefofpancreatitissymptoms.Theindexesofoperationtime,postoperativehospitalstay,perioperativecomplications(bileleakage,bleeding,incisioninfection,bileductinjury,etc.),rateoflaparotomy,totalhospitalstay,totalmedicalexpensesandrecurrencerateofpancreatitiswerecomparedbetweenthetwogroups.ResultsBothgroupsweresuccessfullyoperatedwithoutseriouscomplicationsordeath.Therewerenosignificantdifferencesinperioperativecomplicationrate,rateoflaparotomy,recurrencerateofpa