免疫组化染色对病理技术质量控制的影响分析-国际临床研究杂志.docx

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免疫组化染色对病理技术质量控制的影响分析

【摘要】目的分析在病理技术质量控制中采取免疫组化染色所体现的效果。方法将我院2022年7月至2023年7月这一时段内开展病理检查的患者纳入研究，入组对象共96例。并将所有患者随机进行随机组别划分，其中48例归入对照组，对其实施常规HE染色；另48例归入观察组，对其实施免疫组化染色。从切片质量、确诊情况、病理检验质量对两组作出综合评价。结果观察组相较对照组，其切片质量优良率存在明显提高趋势，两组统计学有显著意义（P＜0.05）。观察组相较对照组，其确诊率存在更明显提高趋势，两组统计学有显著意义（P＜0.05）。观察组相较对照组，其取材质量、染色质量、试剂质量评分存在更明显升高趋势，两组统计学有显著意义（P＜0.05）。结论临床病理检查中采取免疫组化染色可实现病理技术质量大幅提升，保证对疾病确诊率。

【关键词】免疫组化染色；病理技术；质量控制

【收稿日期】2024年2月17日【出刊日期】2024年3月25日【DOI】10.12208/j.ijcrAnalysisofinfluenceofimmunohistochemicalstainingonqualitycontrolofpathologicaltechniques

【Abstract】ObjectiveToanalyzetheeffectofimmunohistochemicalstainingonthequalitycontrolofpathologicaltechniques.MethodsAtotalof96patientswhounderwentpathologicalexaminationinourhospitalfromJuly2022toJuly2023wereincludedinthestudy.Allpatientswererandomlydividedintorandomgroups,48ofwhichwereassignedtothecontrolgroup,androutineHEstainingwasperformedonthem.Another48caseswereassignedtotheobservationgroup,andimmunohistochemicalstainingwasperformedonthem.Thetwogroupswereevaluatedcomprehensivelyfromthequalityofsection,diagnosisandpathologicalexamination.ResultsComparedwiththecontrolgroup,thesectionqualityoftheobservationgrouphadamoreobvioustrendofimprovement,andthetwogroupshadstatisticallysignificantsignificance(P0.05).Comparedwiththecontrolgroup,thediagnosisrateoftheobservationgroupwasmoresignificantlyincreased,andtherewasstatisticallysignificantsignificancebetweenthetwogroups(P0.05).Comparedwiththecontrolgroup,thescoresofsamplequality,stainqualityandreagentqualityintheobservationgroupweremoresignificantlyincreased,withstatisticallysignificantsignificancebetweenthetwogroups(P0.05).ConclusionImmunohistochemicalstaininginclinicopathologicalexaminationcangreatlyimprovethequalityo