产黑色素类杆菌与慢性根尖周炎临床症状的相关性.pdfVIP

产黑色素类杆菌与慢性根尖周炎临床症状的相关性

刘海霞

【摘要】目的:探讨产黑色素类杆菌(BPB)与慢性根尖周炎临床症状的相关性.方法:

采用PCR技术检测30个慢性根尖周炎患牙感染根管内5种BPB的定植情况,单因

素分析5种BPB与慢性根尖周炎临床症状的相关性.结果:牙龈卟啉单胞菌(Pg)、

牙髓卟啉单胞菌(Pe)与慢性根尖周炎的疼痛、肿胀呈正相关(OR2,P0.05),与

叩痛、窦道无相关性;变黑普氏菌(Pn)与慢性根尖周炎的叩痛、肿胀呈正相关

(OR2,P0.05),与疼痛、窦道无相关性;中间普氏菌(Pi)和产黑普氏菌(Pm)与慢性

根尖周炎的疼痛、叩痛、窦道和肿胀均无相关性.结论:Pg、Pe与慢性根尖周炎的

疼痛和肿胀密切相关,Pn与叩痛和肿胀密切相关.尚未发现Pi和Pm与慢性根尖周

炎临床症状的相关性.%AIM:Tostudythecorrelationbetweenblack-

pigmentedbacteroides(BPB)andclinicalsymp-tomsofchronic

periodontitis.METHODS:Thecolonizationof5kindsofBPBin30infected

rootcanalsinpatientswithchronicapicalperiodontitisweredetectedby

16SrDNAPCR.ThecorrelationbetweenBPBandclinicalsymptomof

chronicapicalperiodontitiswasanalyzedbymonofactorialoddsratio,and

theirfunctionsinchronicapicalperiodontitiswerediscussed.RESULTS:The

relationshipbetweenP.g,P.eandpain,swellinginchronicapical

periodontitisshowedpositivecorrelation(OR2,P0.05).Buttherewas

nocorrelationwithpainofpercussionandsinus.Therelationshipbetween

P.nandpainofpercussion,swellinginchronicapicalperiodontitisshowed

positivecorrelation(OR2,P0.05).Butithadnocorrelationwithpain

andsinus.TherewasnocorrelationbetweenP.i,P.mandpain,painof

percussion,sinusandswellinginchronicapicalperiodontitis(P0.05).

CONCLUSION:P.g,P.eandP.nplayanimportantroleinpainand

swellinginchronicperiodontitis.TherewasnocorrelationbetweenP.i,P.

mandclinicalsymptominchronicapicalperiodontitis.

【期刊名称】《牙体牙髓牙周病学杂志》

【年(卷),期】2015(025)009

【总页数】4页(P541-543,533)

【关键词】产黑色素类杆菌;慢性根尖周炎

【作者】刘海霞

【作者单位】中国核工业北京四O一医院,北京102413

【正文语种】中文

【中图分类】R780.2

[DOI]10.15956/j.cnki.chin.j.conserv.dent.2015.09.007

[ChineseJournalofConservativeDentistry,2015,25(9):541]

慢性根尖周炎是根管内以厌氧菌为主的混合感染。尽管100多年前就已证实感染

根管内存在细菌，但到目前为止，有关细菌引起根尖周炎临床症状的发病机制仍存

在分歧。Siqueira[1]、FoschiF[2-3]等认为感染根管内细菌