基于SEER数据库的肿瘤直径大于7.0厘米的非小细胞肺癌患者预后分析.pdf

2021481 Cancer Res Prev Treat,2021,Vol.48,No.149

肿瘤防治研究年第卷第期··

doi:10.3971/j.issn.1000-8578.2021.19.1587临床研究

··

基于SEER数据库的肿瘤直径大于7.0厘米的

非小细胞肺癌患者预后分析

冯婷婷，陈众众，闫文锦，王玉秀，张峻，徐兴祥，陈勇，杨俊俊，闵凌峰

PrognosisAnalysisofNon-smallCellLungCancerwithDiameterover7.0cmBasedon

SEERDatabase

FENG Tingting, CHEN Zhongzhong, YAN Wenjin, WANG Yuxiu, ZHANG Jun,  

XU Xingxiang, CHEN Yong, YANG Junjun, MIN Lingfeng

DepartmentofRespiratoryandCriticalCareMedicine,NorthernJiangsuPeople’s

Hospital,TheFirstClinicalCollegeofDalianMedicalUniversity,ClinicalMedicalCollege

ofYangzhouUniversity,Yangzhou225001,China

CorrespondingAuthor:MINLingfeng,E-mail:*******************

Abstract:Objective To analyze the mortality risk and evaluate the curative effects of surgery and non-

surgery on NSCLC with diameter 7.0 cm. 

Methods We collected the data of NSCLC patients with diameter 

table method. Overall survival curve was estimated by Kaplan-Meier method. Univariate and multivariate Cox 

regression models were used to analyze the independent prognostic factors. 

Results The 1, 2, 3-year survival 

and treatment were the independent prognostic factors (

P0.001).  ConclusionSurgeryisbenefitedforthe

prognosis of stage N0-N1 NSCLC patients with diameter 7.0 cm. And for stage N2 NSCLC patients with 

patients with tumor diameter 

≥9.0cmorlymphnodeN3stagehavenostatisticallysignificantdifferencesin

prognosis. In addition, palliative treatment does not improve the prognosis of patients.

Keywords: Tumor size; NSCLC; Surgery; SEER database; Prognosis

Funding: National Natural Sci