丙泊酚静脉麻醉与安氟醚吸入麻醉在巴马小型猪体外循环中的比较研究.pdfVIP

丙泊酚静脉麻醉与安氟醚吸入麻醉在巴马小型猪体外循环中的

比较研究

陈克研;刁玉刚;金强;王洪乾;姚国泉;张铁铮

【摘要】Theassaywasaimedtocompareofpropofolintravenous

anesthesiaandenfluraneinhalationanesthesiaincardiopulmonarybypass

ofBamaMinipigs.10BamaMinipigs,theaverageintotwogroupswere

propofolintravenousanesthesiaandenfluraneinhalationanesthesia,and

inpreoperative,operativeandpostoperativetheanesthesiamonitoring.

Afteropenningbreast,wholebloodweretreatedwithheparin,thenthe

ascendingaorta,superiorvenacavaandinferiorvenacavawereintuba-ted

respectively,andconnectedtoacardiopulmonarybypassmachinelinethe

CPB.Thevitalsigns,nosetemperature(NT),heartrate(HR),meanarterial

pressure(MAP),pHandbloodoxygensaturation(SPO2)ofeach

experimentalpigswereobserveandrecordedwithinbeforeintrodutionof

anesthesia(TO),afterinductionofanesthesia(T1),immediatelybeforeCPB

(T2),coolingto30℃(T3),blockingtheaortaformerimmediate(T4),

blockingtheaorta4min(T5),startthawingimmediate(T6),stopCPB

immediate(T7),closedchestimmediatelyafter(T8)anddrawingtube

operationover10min(T9).Twogroupsofweightnumberofpigs,

operationtimeandanesthesiatimeallhadnosignificantdifference(P0.

05).Differentfluorineethergrouprestorespontaneousbreathingashort

timeinpropofolgroup(P0.05).Comparedwiththebasicval-ue(T0and

T1),theNT,HRandMAPvalueoftheexperimentpigsweresignificantly

lower(P0.C5).ButeachroomsandinthegroupSPO2valueandpHwere

notsignificantdifferent(P0.05).Propofolintravenousanesthesiaduring

theoperationshouldbebasedontheexperimentalanimalsofthereaction

conditionsappropriateadjustmentspropofolpumpintotheconcentration;

anddifferentfluorineetherinhaledanesthesiaduringtheprocedureof

smooth,anaeestheticeffectwasgood,postoperativecamequickly,

suitableforcomplicatedcases,