中国多省市心血管病危险因素队列研究与美国弗莱明翰心脏研究结果的比较.pdf

20042322ChinJCardiol,Fbruary2004,Vol.32No.2#167#

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刘静赵冬王薇吴桂贤曾哲淳刘军秦兰萍孙佳艺吴兆苏

=(ChinsMult-iProvincialCohort

Study,CMCS),

CMCS35~64301211030~74525112

,10

CMCS(1)CMCS10

115%016%,810%218%(2)CMCS

(HDL-C),

(3)(RR),CMCS

RR;CMCS(TC)5120~6123mmoPlLHDL-C

0191mmoPlLRR,RR

(4)CMCS

CMCSROC0173601705,0175901742

(5)CMCS,

CMCS,CMCS

,CMCS10

CMCS

CMCS,

=;;

ComparisonbetweentheresultsfromtheChineseMult-iprovincialCohortStudyandthosefromthe

FraminghamHeartStudyLIUJing,ZHAODong,WANGWei,WUGui-xian,ZENGZhe-chun,LIUJun,

QINLan-ping,SUNJia-yi,WUZhao-su.DepatmentofEpidemiology,BeijingInstituteofHeat,Lungand

BloodVesselDiseases,Bejiing100029,China

Coespondingautho:LIUJing,Email:jingliu0516@yahoo.com.cn

=AbstractObjectiveTovaluatthvalidationofincorporatingthFraminghamprdicationmodlin

Chinspopulation,bycomparingthrsultsfromChinsMulti-provincialCohortStudy(CMCS)withthrsults

fromthFraminghamStudy.MethodsInCMCS,30121participantsofHanthnic,agd35to64yars,wr

rcruitdfrom11provincsinChina1ThsubjctsofthFraminghamHartStudywr5251whitAmricansin

Framingham,Massachustts,US,whowr30-74yarsoldatbaslin1Th10-yar/hard0CHDrisk,baslin

riskfactors,thassociationofriskfactorswithCHDinthtwocohorts,aswllasthprformancofCMCSmodl

andthFraminghammodlinthisChinspopulationwrcompard1Results(1)Th10-yarhardCHDrisks

wrmuchlowrinCMCScohort(115%formnand016%forwomn,rspctivly),compardw