爱必妥使用方法及不良反应管理PPT课件.pptxVIP

爱必妥使用方法及不良反应管理

CN-ERBMCRC-00221AeRCV

·爱必妥使用方法

·爱必妥皮肤反应管理

·爱必妥口腔黏膜炎管理

目录

MeRCK

mFOLFOX61,2,39

Oxaliplatin85mg/mIVday1*

Leucovorin400mg/m²IVday1*

5-FU400mg/m²IVbolusonday1,then1200mg/m²ldx2days

(total2400mg/m²over46-48hours)IVcontinuousinfusion

Repeatevery2weeks

mFOLFOX74

Oxaliplatin85mg/m²IVday1*

Leucovorin400mg/m²IVday1

Icontinuousinfusior

Repeatevery2weeks

FOLFOX+bevacizumab5.1

Bevacizumab5mg/kgIV,day1

Repeatevery2weeks

FOLFOX+panitumumab⁶(KRAS/NRAS/BRAFWTonly)Panitumumab6mg/kgIVover60minutes,day1

Repeatevery2weeks

FOLFOX+cetuximab⁷(KRAS/NRAS/BRAFWTonly)

Cetuximab400mg/m²IVover2hoursfirstinfusion,

then250mg/m²IVover60minutesweekly

orCetuximab500mg/m²IVover2hours,day1,every2weeks

CAPEOX8

Oxaliplatin130mgim²IVday!*

Capecitabine1000¹mg/m²twicedailyPOfor14daysRepeatevery3weeks

CAPEOX+bevacizumab8,t.I

Oxallplatin130mgim²IVday1*

Repeatevery3weeks

FOLFIRI9,10

Irinotecan180mgim²IVover30-90minutes,day1

Leucovorin**400mg/m²IVinfusiontomatchdurationofirinotecan

infusion,day1

5-FU400mg/m²IVbolusday1,then1200mgim²ldx2days(total

2400mg/m²over46-48hours)continuousinfusion

Repeatevery2weeks

FOLFIRI+bevacizumab11,+,I

Bevacizumab5mg/kgIV,day1

Repeatevery2weeks

·初始剂量400mg/m2

·每周剂量250mg/m2·输注

NCCNGuidelinesVersion4.2019ColonCancer

剂量和给药

PitedbyYanhngLnon1PM.FaupesonalseonyNdtappoedtodstoutonCoprignte2018NatonlompethenaheCamerNebo0A,Ina,ARagtReserved.

5-FU1200mgim²ldx2days(total2400mgim²over46-48hours)

NCCNGuidelinesIndexTableofContents Discussion

SYSTEMICTHERAPYFORADVANCEDORMETASTATICDISEASE-CHEMOTHERAPYREGIMENS

Capecitabine1000tmg/m²POtwicedailyfor14days

National

ComprehensiveCancer

Network

·每周给药

Bevacizumab7.5mg/kgIVday1

MeRCK

·药品应贮存在2℃-8℃的冷柜中，禁止冰冻!

·未开封的药品保