CXCR4-antagonist-10-生命科学试剂-MCE.pdf

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CXCR4antagonist10

Cat.No.:HY-168095

CASNo.:3056005-98-9

分⼦式:C₄₄H₆₂N₁₆O₁₀

分⼦量:975.06

Sequence:Ac-Arg-Ala-{Dap}-Arg-{2-Nal}-His-Glu

SequenceShortening:Ac-RA-{Dap}-R-{2-Nal}-HE

作⽤靶点:CXCR

作⽤通路:GPCR/GProtein;Immunology/Inflammation

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性CXCR4antagonist10(compound21)是⼀种有效的CXCR4拮抗剂，其IC50为7.8nM。CXCR4antagonist

10在癌症研究中发挥着重要作⽤。

IC50TargetCXCR4

7.8nM(IC50)

REFERENCES

[1].AnnaMariaTrotta,etal.ComprehensivestructuralinvestigationofapotentandselectiveCXCR4antagonistviacrosslinkmodification.

EurJMedChem.2024Sep25:279:116911.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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