天香丹颗粒对冠心病心绞痛(痰瘀互阻型)患者的影响 .pdfVIP

天香丹颗粒对冠心病心绞痛(痰瘀互阻型)患者的影响

李超;朱小莉;安冬青;彭雪梅

【摘要】ObjectiveToinvestigatetheimpactofTianxiangdangranuleson

coronaryheartdiseaseandanginapectorispatientsperformedasTCM

syndromeofphlegmstasis.MethodsAtotalof70coronaryheartdisease

andanginapectorispatientsperformedasTCMsyndromeofphlegm

stasiswereselectedinTCMHospitalAffiliatedtoXinjiangMedical

UniversityfromJune2015toJuly2016,andtheyweredividedintocontrol

groupandobservationgroupaccordingtorandomnumbertable,eachof

35cases.Basedonconventionaltreatment,patientsofcontrolgroup

receivedxinkeshutablets,whilepatientsofobservationgroupreceived

Tianxiangdangranulesbasedonthatofcontrolgroup;bothgroups

continuouslytreatedfor4weeks.TCMsymptomsscore,serumlevelsof

TNF-α,IL-6andINF-γbeforeandaftertreatment,andECGimprovement

werecomparedbetweenthetwogroups.ResultsNostatisticallysignificant

differencesofchestdistressscore,unmeantchestdullpainscore,feeble

pulsescore,slipperypulsescore,anhelationandlackinginstrength

score,limbsheavinessscore,dull-redorecchymotictonguebodyscorewas

foundbetweenthetwogroupsbeforetreatment(P＞0.05),whilechest

distressscore,unmeantchestdullpainscore,feeblepulsescore,slippery

pulsescore,anhelationandlackinginstrengthscore,limbsheaviness

score,dull-redorecchymotictonguebodyscoreinobservationgroupwere

statisticallysignificantlylowerthanthoseincontrolgroupaftertreatment

(P＞0.05).NostatisticallysignificantdifferenceofserumlevelofTNF-α,IL-

6orINF-γwasfoundbetweenthetwogroupsbeforetreatment(P＞

0.05),whileserumlevelsofTNF-α,IL-6andINF-γinobservationgroupwere

statisticallysignificantlylowerthanthoseincontrolgroupaftertreatment

(P＜0.05).ECGimprovementrateinobservationgroupwasstatistically

significantlyhigherthanthatincontrolgroup(P＜0.05).Conclusion

Tianxian