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GastrointestinalViruses
ViralGastroenteritisItisthoughtthatvirusesareresponsibleforupto3/4ofallinfectivediarrhoeas.1Viralgastroenteritisisthesecondmostmonviralillnessafterupperrespiratorytractinfection.2Indevelopingcountries,viralgastroenteritisisamajorkillerofinfantswhoareundernourished.Rotavirusesareresponsibleforhalfamilliondeathsayear.3Manydifferenttypesofvirusesarefoundinthegutbutonlysomeareassociatedwithgastroenteritis.4
AssociatedwithgastroenteritisRotavirusesAdenoviruses4041Caliciviruses嵌杯病毒NorwalklikevirusesorSRSV(SmallRoundStructuredViruses)AstrovirusesSRV(SmallRoundViruses)CoronavirusesToroviruses
Foundinthegut,notnormallyassociatedwithgastroenteritisPolioCoxsackieACoxsackieBEchoEnteroviruses68-71HepatitisAHepatitisEAdenoviruses1-39Reoviruses
FoundinthegutasopportunisticinfectionCMVHSVVZVHIV
GastrointestinalVirusesVirusGenomeTypicaldiseaseincubationDurationRotaviruses:GroupA,B,Cds-segmentedRNAMajorcauseofdiarrheainchildren1-3days24-56h5-8days3-7daysCalicivirusesNorwalkagentsssRNAInfectsadultsandchildrenEpidemicviralgastroenteritis1-3days18-24h1-3days12-48hEAd40,41LineardsRNAdiarrheainchildren7-8days8-12dAstrovirus+ssRNAInfectsmainlychildrenandelderly1-4days1-4d
GastrointestinalVirusesInfants:RotavirusA;Adenovirus40,41;CoxsackieA24virusInfants,children,andadultsNorwalkvirus;Calicivirus嵌杯病毒;astrovirus;RotavirusB;Reovirus.
HumanRotavirus
ImportantCharacteristicsnmround,doubleshelled,enclosingagenomeof11segmentsofdoublestrandedRNA.”
GroupsofRotavirusesGroupAsubtypes1,2,3,4(mainhumanpathogens)
(Further7subtypes)alsoinfectanimals(monkey,calf,mouse)GroupBInfectspigsandrats
FoundtocauseextensiveoutbreaksinChinainpastdecadeGroupCInfectsPigs(OccasionallyMan)GroupDInfectsbirdsGroupEInfectspigs
Essentiallyaningestiondisease(faeca
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