急性冠脉综合征糖代谢异常与冠状动脉病变程度的关系探讨.pdf

临床研究2010年12月第17卷第36期

急性冠脉综合征糖代谢异常与冠状动脉病变程度的

关系探讨

史宏伟

(山西省大同煤矿集团公司总医院心内科，IJJ西大同037003)

摘【要1目的：探讨急性冠脉综合征(ACS)患者糖代谢异常与冠状动脉病变程度的关系。方法：对190例急性冠脉综

合征患者做葡萄糖耐量试验，根据血糖水平依次分为糖耐量正常A组、糖耐量异常B组、糖尿病C组。利用冠状动

脉造影确定冠状动脉病变严重程度。结果：在ACS患者中，合并糖代谢异常的患者占总数的71．6％，约占2／3；糖代谢

异常组的冠状动脉造影显示病变更为严重，多支血管病变的发生率明显高于糖耐量正常组；多支血管病变的发生率

在糖耐量异常和糖尿病组间差异无统计学意义。结论：合并糖代谢异常的ACS患者冠脉病变程度更为严重。

关『键词1急性冠脉综合征；糖代谢异常；口服糖耐量试验

中『图分类号】R543．3[文献标识码]A文【章编号】1674～4721(2010)12(c)一026—02

Discussacutecoronarysyndromesugarmetabolismdisordersandcoronary

lesionsdegreeofrelationship

SHIHongwei

(DepartmentofHeartMedicine，DatongCoalGroupCompanyGeneralHospitalofShanxiProvince，ShanxiProvince，Da—

tong037003，China)

A【bstract]Objective：Toexploretherelationshipbetweenglycometabolismdysfunctionandthedegreeofcoronaryartery

lesioninpatientswithacutecoronarysyndrome．Methods：Atotalof190enrolledACSpatientswereexaminedbyoralglu—

cosetolerancetest(OGTY)anddividedintothreegroups：groupA(normalglucosetolerance)，groupB(abnormalglucosetol—

eranee)andgroupC(diabetesmellitus)accordingtothebloodglucoselevels．Theseverityofcoronaryarterylesionswasde—

teminedusingcoronaryangiography．Results：TheACSpatientsmergerwithabnomralglucosemetabolismtotal71．6％．

about2／3；Sugarmetabolicabnomralitiesgroupofcoronaryangiographyshowedlesionswasmoreserious，theincidenceof

muhivesselvascularlesionswasobviouslyhigherthanthatofnomralglucosetolerance；Theincidenceofmuhivesselvascu—

larlesionswithabnormalglucosetoleranceanddiabetescomparativedifferencesbetweengroupswerestatisticallysignifi—

cant．Conclusion：ComparedwiththoseintheACSpatientswithnomalglucosetolerance，coronaryarterylesionsinACS

patientswithabnomalglucosemetabolismaremoresever