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LearningObjectivesTomasterthecauseofpepticulcerclinicalmanifestationsandcomplications;Tomasterthepepticulcernursinginterventionandhealtheducation;Befamiliarwiththekeypointsofthepathogenesisandtreatmentofpepticulcer;
DefinitionAcircumscribedulcerationofthegastrointestinalmucosaoccurringinareasexposedtoacidandpepsinandmostoftencausedbyHelicobacterpyloriinfection.(UpholdGraham,2023)
PepticUlcers:
GastricDudodenal
PepticUlcers:
GastricDuodenalgastriculcer:theulcerthatoccursinthestomachlining,someofthemmaybemalignant.duodenalulcer:mostoftenseeninfirstportionofduodenum.
GU
DU
PUDDemographics(流行病学)Lifetimeprevalenceis~10%.Theincidenceofduodenalis4timesascommonasgastriculcermostcommoninmiddleagepeak30-50yearsMaletofemaleratio—4:1
Etiology(病因学)Helicobacterpylori(HP)
Etiology(病因学)nonsteriodalanti-inflammatorydrugs(NSAID)AcidandpepsinOthers
diseasecharacteristicsChronicprocessperiodicalattackRhythmicabdominalpain
mainsymptom(1)abdominalpain:theclassicsymptomofPUD.Pain—”gnawing”,“aching”,or“burning”“hungerlike”(钝痛、胀痛、灼痛或饥饿痛)(2)rhythmicity:GUEating-pain-reliefDUpain-eating-relief(3)cyclicity:Attackmoreinautumnorwinter
gastriculcerduodenalulcertimepositionnatureruleoccurs0.5~1hourafteramealandreliefuntilnextmeal,maynotawakenpatientfromsleep.medianorleftofSubxiphoidburningpainorcrampypainEating-pain-reliefoccurs3-4hoursafteramealandmayawakenpatientfromsleep.Midlineorrightofepigastrichungerlikepainorburningpainpain-eating-reliefPaincharacteristicsofpepticulcer
ClinicalmanifestationOthersymptomsofdigestivesystem:Nausea,vomiting,belching,bloating,chestdiscomfortmayalsooccur.
Clinicalmanifestation
signEpigastrictenderness
Complicationshemorrhage
ComplicationsP
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