艾滋病病毒王利沙HIV讲解.pptx

艾滋病病毒主讲老师：王利沙HIVWeifangNursingVocationalCollege潍坊护理职业学院

艾滋病病毒HIV李某，45岁，自感嗜睡、盗汗、乏力、气促半年，最近加重伴咳嗽15天，持续发热、胸痛胸闷，伴有明显体重下降。体检：颈部、耳后淋巴结肿大，出现口腔白斑。胸部CT提示：双肺可疑絮状模糊阴影；实验室检查：WBC7.67×109/L；HIV抗体阳性。诊断为：艾滋病。案例CaseLi,45yearsold,hasbeenexperiencingdrowsiness,nightsweats,fatigue,andshortnessofbreathforsixmonths.Recently,hehasbeenworseningwithcoughfor15days,persistentfever,chestpain,andsignificantweightloss.Physicalexamination:Enlargementoflymphnodesintheneckandbehindtheears,andappearanceoforalleukoplakia.ChestCTscanshowssuspiciousfuzzyopacitiesinbothlungs;Laboratorytest:WBC7.67×109/L;HIVantibodypositive.Thediagnosiswas:AIDS.请问：Excuseme：1.艾滋病人有哪些典型的临床表现？1.Whatdiseaseisthepatientmostlikelytohave?2.HIV感染的主要途径有哪些？2.Whatisthecauseofthisdisease?

超级癌症：艾滋病SuperCancer:AIDS艾滋病病毒HIV引起AIDS的病原体是人类免疫缺陷病毒（HIV）。ThepathogenthatcausesAIDSisthehumanimmunodeficiencyvirus(HIV).“超级癌症”之称，其潜伏期长、传播速度快、病情凶险、致死率高。Knownassupercancer,ithasalongincubationperiod,fasttransmissionspeed,dangerouscondition,andhighmortalityrate.为提高人们对艾滋病的认识，WHO将每年的12月1日定为世界艾滋病日。InordertoraisepeoplesawarenessofAIDS,WHOhasdesignatedDecember1everyyearasWorldAIDSDay.

01生物学性状Biologicaltraits

生物学性状Biologicaltraits形态与结构Morphologicalstructure中等大小球形颗粒Mediumsizedsphericalparticles核心为RNA.ThecoreisRNA有包膜Thereisacapsule

生物学性状Biologicaltraits形态与结构Morphologicalstructure体外培养：仅感染表面有CD4分子的T细胞和巨噬细胞。Invitroculture:onlyinfectTcellsandmacrophageswithCD4moleculesontheirsurface.实验培养：实验室常用新鲜分离的正常人T细胞或用患者自身分离的T细胞培养病毒。黑猩猩和恒河猴可作为HIV感染的动物模型，但其感染过程和症状与人不同。Experimentalcultivation:ThelaboratorycommonlyusesfreshlyisolatednormalhumanTcellsorviruscultivationusingTcellsisolatedfrompatientsthemselves.ChimpanzeesandrhesusmonkeyscanserveasanimalmodelsforHIVinfection,buttheirinfectionprocessandsymptomsaredifferen