P160-peptide-生命科学试剂-MCE.pdf

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P160peptide

Cat.No.:HY-P10789

CASNo.:362043-77-4

分⼦式:C₇₄H₁₀₅N₁₇O₁₇S

分⼦量:1536.79

Sequence:Val-Pro-Trp-Met-Glu-Pro-Ala-Tyr-Gln-Arg-Phe-Leu

SequenceShortening:VPWMEPAYQRFL

作⽤靶点:Microtubule/Tubulin

作⽤通路:CellCycle/DNADamage;Cytoskeleton

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性P160peptide是⼀种乳腺癌靶向肽，与乳腺癌细胞中的⾓蛋⽩1(KRT1)受体结合，Kd约1.1μM，具有显著

的靶向乳腺癌细胞的药物递送潜⼒。P160peptide能够提⾼前促凋亡抗微⽣物肽MccJ25(microcinJ25)的细

胞摄取率和抗癌活性。P160peptide可⽤于抗癌领域研究[1]。

REFERENCES

[1].SoudyR,etal.BreastCancerTargetingPeptideBindsKeratin1:ANewMolecularMarkerforTargetedDrugDeliverytoBreastCancer.

MolPharm.2017Mar6;14(3):593-604.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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