腹腔高压症及腹腔压力监测在危重病人中的应用.ppt

*其结果是导致每搏输出量的减少而代偿性的使心率增快和MAP下降。*CVP的升高反应了腔静脉和心脏的受压。*Fig.1.Centralvenouspressure(CVP)(meanSD)ofpigswithnormal(control)andelevatedintra-abdominalpressure(IAP-30).NotethatCVPwassignificantlyincreasedwiththeincreaseofIAP.Timeintervalschangedfrom1to4hoursafterabreakat4hours.*Significantdifferencecomparedwithbaseline:p0.0023(4hours).?Significantdifferencecomparedwithcorrespondingcontrol:p0.001(2hours).ANOVAandposthocanalysis:p0.001.Fig.7.Cardiacoutput(meanSD)ofpigswithnormal(control)andelevatedintra-abdominalpressure(IAP-30).NotethatcardiacoutputwasdecreasedinthepresenceofanIAPof30mmHg.*Significantdifferencecomparedwithbaselinevalueaccordingtopairedttest,p0.0067(IAP-30after4hours)and0.0058(controlafter12hours).?Significantdifferencecomparedwithcorrespondingcontrolvalueaccordingtounpairedttest,p0.001after12hours.ANOVAandposthocanalysis:p0.002.*Fig.4.Intrathoracicbloodvolume(ITBV)(meanSD)ofpigswithnormal(control)andelevatedintra-abdominalpressure(IAP-30).NotethatITBVwassignificantlydecreasedafter20hoursand24hoursinthestudygroup.*Significantdifferencecomparedwithbaselinevalueaccordingtopairedttest,p0.003after20hours.?Significantdifferencecomparedwithcorrespondingcontrolvalueaccordingtounpairedttest,p0.001after20hours.ANOVAandposthocanalysis:p0.01.Fig.5.Totalcirculatingbloodvolume(TBV)(meanSD)ofpigswithnormal(control)andelevatedintra-abdominalpressure(IAP-30).TheTBVwassignificantlydecreasedafter20hoursand24hoursinthestudygroup.*Significantdifferencecomparedwithbaselinevalueaccordingtopairedttest,p0.003.?Significantdifferencecomparedwithcorrespondingcontrolvalueaccordingtounpairedttest,p0.021after20hours.ANOVAandposthocanalysis:p0.085.*Fig.9.Correlation