五年制LABORATORY DIAGNOSTICS医学课件.ppt

五年制1单核细胞减少(Monocytopenia)：相对性减少：再障五年制1NormalWBC五年制1（一）白细胞形态中性粒细胞形态异常（granulationanomaliesandinclusions）＊中性粒细胞核象变化（N-nuclearphase）＊中性粒细胞中毒性改变异型淋巴细胞（atypicallymphocyte）五年制1N-nuclearphase:核左移（nuclearleftShift）■DefinitionThestab（juvenilegranulocytes）5%■Interpretation①acutepyogenicinfection②acutepoisoning③bleeding④hemolyticreaction,etc.五年制1N-nuclearphase:核右移（nuclearrightleft）■Definitionfiveormorelobes(Nsg)3%.■Interpretation①MA②antimetabolicdrugs五年制1N-pathologicalmorphology(1)N-toxicchange:variableinsizetoxicgranulesvacuolizationnucleardegeneration五年制1toxicgranulesvacuolization五年制1N-toxicchange■Interpretation（severe）pyogenicinfectionmalignanttumoracutepoisoningextensiveburn,etc.五年制1N-pathologicalmorphology（2）分叶过多(hypersegmentation)：■Definitionfivelobes(Nsg)■Interpretation①MA②antimetabolicdrugs五年制1N-pathologicalmorphology(3)Auerbodies(Auerrod)■InterpretationLeukemiaandthetype:AML(+);(急粒,急单)ALL(-).五年制1Atypicallymphocyte■Type：Ⅰ;Ⅱ;Ⅲ.五年制1AtypicallymphocyteInterpretation■Physiologic■Pathologic①infectious:Virus(EBV,infectiousmononucleosis,10%),②Drugallergy③Afterbloodtransfusion④Others:immunologicaldisease,etc五年制1参考文献：＜诊断学＞陈文斌人民卫生出版社２００１，７＜实验诊断学图谱＞张丽霞上海科学技术出版社２００２，６五年制1*一学时五年制1LABORATORY

DIAGNOSTICS五年制1Whatislaboratorydiagnostics医生的医嘱通过临床实验室分析所得到的信息为预防、诊断、治疗疾病和预后评价所用的医学临床活动。医学检验=？=检验医学五年制1INTRODUCTIONThehistoryoflaboratorydiagnostics★handiworkautomationTLA★moderninstrumentsandequipments(RIA,EIA,PCR,FCM,etc)