脑脊液浆膜腔积液检查课件.ppt

OutlineCSF:colourlessliquidthatflowsthroughthefourcerebralventricles,subarachnoidspaceandspinalcanalsurroundingthebrainandspinalcord.CSFcirlulationcommunicatewithbloodcirculationAdult:90—150mlNewborn:10—60ml

bloodbrainbarrier

AIMS中枢神经感染性疾病的诊断与鉴别诊断。脑血管疾病的诊断与鉴别诊断。协助脑部肿瘤的诊断。中枢神经系统疾病的治疗与疗效观察。

ContentsofexaminationGeneralProperties：pressure、color、Transparency、ClotsandfilmChemicalExamination：protein、glucose、chlorideMicroscopyBacteriologicalExamination

PressureGeneralPropertiesAdult(lying):80—180mmH2O，40-50drips/minchildren：40-100mmH2O。Increase：IntracranialInflammation：meningitis,cephalitis,myelitiscerebraledema,cerebralhemorrhage,braintumorsExtracranial：hypertension,congestiveheartfailureDecrease:CSFcirculationobstruction,lossorimpairmentinsecretion

ColorchangesColorofCSFConditionsorcausesClear,colorlessnormalMilkyWithWBCincreasePinktoyellowWithbloodYellowHyperbilirubinemiaProtein≥1.5g/LGreenPurulentCSFBrowntoBlackMeningealmelanoma

TransparencyNormal:Clear,colorlessClearorCloudy：ViralMeningitis、EpidemicEncephalitisBorSyphilisinCNSGroundglassopacity：TuberculousMeningitisMilkyturbid：PurulentMeningitis

ClotsandfilmNormal:Noclotsorfilmin24hoursPurulentMeningitis:clotsobservedin1-2hoursTuberculousMeningitis:thinfilmcoverafter12—24hoursSubarachnoidobstruction:yellowjelly

ProteinQualitative：Pandytest：-/±Quantitative：0.15～0.45g/L(adult,lumbarpuncture)++++++++++Chemicalexamination

Clinicalsignificanceinflammation：PM:↑↑↑TM:↑↑VM:↑Hemorrhageincranialorsubarachnoidintracranialmasslesions：tumor,hematomamultiplesclerosis,neurosyphilis

GlucoseinCSFNormalvalue:Adult:2.5—4.5mmol/LChild:3.1—4.5mmol/LGCSF/GP：0.3—0.9

ClinicalsignificanceInflammation：PM:↓↓↓TM:↓VM：normalIntracranialtumor,neurosyphilisHypoglycemia

ChlorideinCSFAdult：120—130mmol/LTM：↓↓↓，102mmol/LPM：102—116mmol/L。Hypochloremia，suchasseverevomit、diarrhea,