5针法A型肉毒杆菌毒素注射在治疗膀胱过度活动症中的应用研究.docx

5针法A型肉毒杆菌毒素注射在治疗膀胱过度活动症中的应用研究

李军华宋晨周鹏潘慧仙

[关键词]?膀胱过度活动症；A型肉毒毒素；问卷调查；重复注射

[中图分类号]?R574????[文献标识码]?A????[DOI]?10.3969/j.issn.1673-9701.2024.08.013

5?Application?of?botulinum?toxin?A?injection?in?overactive?bladder

LI?Junhua，?SONG?Chen，?ZHOU?Peng，?PAN?Huixian

Department?of?Urology，?Hangzhou?Third?Peoples?Hospital，?Hangzhou?310009，?Zhejiang，?China

[Abstract]?Objective?To?compare?and?analyze?the?efficacy?and?safety?of?5-needle?injection?and?standard?20-needle?injection?in?the?treatment?of?overactive?bladder?with?botulinum?toxin?type?A.?Methods?A?retrospective?analysis?was?performed?on?48?patients?with?overactive?bladder?who?received?intravesical?injection?of?botulinum?toxin?type?A?in?the?Department?of?Urology，?Hangzhou?Third?Peoples?Hospital?from?January?2015?to?December?2022，?and?they?were?divided?into?two?groups?according?to?the?number?of?injections，?with?24?patients?in?each?group.?The?observation?group?received?5-needle?injection，?and?the?control?group?received?standard?20-needle?injection.?Average?daily?frequency?of?urination，?international?consultation?on?incontinence?questionnaire-?overactive?bladder，?international?consultation?on?incontinence?questionnaire-overactive?bladder?（ICIQ-OAB）?score，?overactive?bladder?（OAB-Q）?score，?visual?analogue?scale?（VAS），?patient?generated?index?（PGI-I）?score，?complication?rate?and?willingness?to?repeat?injection?were?recorded?before?and?after?treatment?in?two?groups，?respectively.?Results?There?were?no?significant?differences?in?age，?gender，?course?of?disease，?average?daily?frequency?of?urination?before?treatment?and?baseline?data?of?each?score?between?the?two?groups，?which?were?comparable.?All?patients?completed?treatment，?and?compared?with?before?treatment，?the?mean?daily?frequency?of?urination，?ICIQ-OAB?and?OAB-Q?were?improved?after?treatment?（P0.05），?there?was?no?significant?difference?between?the?two?groups?（P?0.05）.?There?were?no?significant?differences?in?scores?and?incidence?of?complications?between?the?two?groups?aft