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脑白质高信号严重程度与络病学证型分布研究
[关键词]络病学;辨证分型;脑白质高信号;脑小血管病
[中图分类号]R743;R224[文献标识码]A[DOI]10.3969/j.issn.1673-9701.2025.02.001
Correlatingwhitematterhyperintensitiesseveritywithcollateraldiseasesyndrometypedistribution
ZHANJianhu1,QIUWeiwen2,LANHaiyuan3,WANGHuaqiang2
1.TheThirdClinicalMedicalCollegeofZhejiangChineseMedicalUniversity,Hangzhou310053,ZhejiangChina;2.DepartmentofNeurology,LishuiTCMHospitalAffiliatedtoZhejiangChineseMedicalUniversity,Lishui323000,ZhejiangChina;3.DepartmentofRadiology,LishuiTCMHospitalAffiliatedtoZhejiangChineseMedicalUniversity,Lishui323000,ZhejiangChina
[Abstract]ObjectiveToexploretherelationshipbetweentheseverityofwhitematterhyperintensities(WMH)andthedistributionofcollateraldiseasesyndrometypes.MethodsAtotalof208patientsclearlydiagnosedwithcerebralsmallvesseldiseaseinLishuiTCMHospitalAffiliatedtoZhejiangChineseMedicalUniversityfromDecember2022toDecember2023wereselectedasthestudysubjects.Allenrolledsubjectsinthestudycompletedthecollateraldiseasesyndromedifferentiation.WMHwasgradedonmagneticresonancenbsp;imagingfluid-attenuatedinversionrecovery(FLAIR)sequencesusingtheFazekasscaleandmeasuredforvolume.ResultsAmongthe208patients,therewere52casesofthebraincollateralimpoverishment(BCI)type,withFazekasscoreof3(2,3)points,andWMHvolumeof(8.80±9.37)ml;67casesofthebraincollateralstasis(BCS)type,withFazekasscoreof4(3,4)points,andWMHvolumeof(13.42±9.18)ml;47casesofthebraincollateralconstraint(BCC)type,withFazekasscoreof4(3,5)points,andWMHvolumeof(14.60±10.07)ml;and42casesofthebraincollateralocclusion(BCO)type,withFazekasscoreof4(4,5)points,andWMHvolumeof(18.65±10.71)ml.Ofthese,55patientswithaFazekasscoreof1-2pointsweremostcommonlyoftheBCItype,105patientswithaFazekasscoreof3-4pointsweremostcommonlyoftheBCStype,and48patientswithaFazekasscoreof5-6pointsweremostcommonlyoftheBCOtype.TherewerestatisticallysignificantdifferencesinFazekasscoresandWMHvolumesbetweentheBCIandBCOtypesandothersyndrometypes(Plt;0.05).ConclusionTheseverityofWMHcorrespondstoacertaindistributio
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