直肠癌术后吻合口漏相关危险因素分析.docx

直肠癌术后吻合口漏相关危险因素分析

程辉郭明晓

[关键词]?直肠癌；吻合口漏；危险因素

[中图分类号]?R735.37??????[文献标识码]?A??????[DOI]?10.3969/j.issn.1673-9701.2024.04.006

Analysis?of?risk?factors?related?to?anastomotic?leakage?after?rectal?cancer?surgery

CHENG?Hui1，2，?GUO?Mingxiao2

1.Postgraduate?Training?Base?of?Linyi?Peoples?Hospital?of?Jinzhou?Medical?University，?Linyi?276000，?Shandong，?China;?2.Department?of?General?Surgery，?Linyi?Peoples?Hospital，?Linyi?276000，?Shandong，?China

[Abstract]?Objective?To?investigate?the?risk?factors?related?to?postoperative?anastomotic?leakage?（AL）?of?rectal?cancer.?Methods?The?clinical?data?of?392?patients?with?rectal?cancer?diagnosed?and?treated?in?Linyi?Peoples?Hospital?from?January?2019?to?December?2021?were?retrospectively?analyzed.?They?were?divided?into?AL?group?（n=17）?and?non-AL?group?（n=375）?according?to?whether?AL?occurred.?The?relevant?clinical?data?of?patients?were?collected，?and?the?risk?factors?of?postoperative?AL?in?rectal?cancer?patients?were?analyzed?by?binary?Logistic?regression.?Results?The?proportion?of?body?mass?index?（BMI）?≥25kg/m2，?preoperative?intestinal?obstruction，?perioperative?blood?transfusion?history，?operation?duration?≥3h?and?postoperative?white?blood?cell?count?≥10×109/L?in?AL?group?were?significantly?higher?than?those?in?non-AL?group?（P0.05）.?Binary?Logistic?regression?analysis?showed?that?BMI≥25kg/m2，?preoperative?intestinal?obstruction，?and?operation?duration?≥3h?were?all?independent?risk?factors?for?postoperative?AL?in?rectal?cancer?patients?（P0.05）.?Conclusion?Patients?with?rectal?cancer?who?are?obese，?have?preoperative?intestinal?obstruction，?and?have?long?operation?duration?have?a?higher?risk?of?postoperative?AL.?Corresponding?preventive?measures?should?be?taken?according?to?the?above?risk?factors?to?reduce?the?incidence?of?AL?and?improve?the?quality?of?life?of?patients.

[Key?words]?Rectal?cancer;?Anastomotic?leakage;?Risk?factor

1??资料与方法

1.1??一般资料

1.2??观察指标

1.3??AL的诊断方法

1.4??统计学方法

所有数据均采用SPSS?25.0统计软件进行分析处理。计数资料以例数（百分率）[n（%）]表示，组间比较采用χ2